Extreme climate events, such as persistent heavy rainfall, cold wave activity, have caused significant damage of ecological environment, economic losses, and adverse social consequences in China, with far-reaching impacts on the increasingly globalizedworld. This talk will focus on these extreme climate events in China under recent global warming, discuss their possible mechanism, potential predictability on subseasonal time scale based on S2S dynamical models, as well as from the view of impacts of annual cycle anomalies of East Asian monsoon.